Frequency of sister chromatid exchange and hematological effects in pesticide-exposed greenhouse sprayers
نویسندگان
چکیده
منابع مشابه
Automatic measurement of sister chromatid exchange frequency.
An automatic system for detecting and counting sister chromatid exchanges in human chromosomes has been developed. Metaphase chromosomes from lymphocytes which had incorporated 5-bromodeoxyuridine for two replication cycles were treated with the dye 33258 Hoechst and photodegraded so that the sister chromatids exhibited differential Giemsa staining. A computer-controlled television-microscope s...
متن کاملMicronucleus and Sister Chromatid Exchange Frequency in Endemic Fluorosis
Inhabitants of the Hohhot Region in Inner Mongolia who drink highfluoride (4-15 mg/L) water were compared for their micronucleus (MN) rate and sister chromatid exchange (SCE) frequency in their peripheral blood lymphocytes. In persons with fluorosis as well as those considered "healthy", the MN rate and SCE frequency were significantly higher (t test) than in a neighbouring control group drinki...
متن کاملSister chromatid exchange analysis in some Holstein bulls
Chromosomal appearance of 12 Holstein bulls selected for artificial inseminations were examined bysister chromatid exchanges (SCEs). For differential staining of sister chromatids bromodeoxyuridine (BrdU)was inoculated in lymphocyte cultures. The mean, maximum and minimum number of SCE per cell weredetermined 6.8 ± 1.14, 8.3 ± 1.1 and 5.7 ± 1.5, respectively. SCE frequencies of all animals were...
متن کاملSister chromatid exchange in cancer.
Sister chromatid exchange (SCE) techniques have been shown to have great potential for use in the in vitro screening of suspected mutagens and carcinogens. Application of these techniques to bone marrow cells and/or lymphocytes from patients with various hematologic malignancies has demonstrated significant abnormalities in SCE frequencies in some of these diseases, as well as showing drug trea...
متن کاملIncreased sister chromatid exchange in peripheral blood lymphocytes from humans exposed to pesticide: evidence based on a meta-analysis.
BACKGROUND Sister chromatid exchange (SCE) in human peripheral blood lymphocytes is one of the most extensively studied biomarkers employed to evaluate genetic damage subsequent to pesticide exposure. OBJECTIVE To estimate the pooled levels of SCE in human peripheral blood lymphocytes among population exposed to pesticide. MATERIALS AND METHODS Meta-analysis on the association between SCE f...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Work, Environment & Health
سال: 1995
ISSN: 0355-3140,1795-990X
DOI: 10.5271/sjweh.39